53rd Carolinas Senior Four-Ball Championship
1. Champions of the Carolinas Senior Four-Ball since 2011.
Patrick Brady, Gary Brown, Ron Carpenter, John Elam, Don Detweiler, Frank Ford III, Mike Gravely, Jim Grainger, Steve Harwell, Kevin King, Jim Pearson, Arlis Pike, Michael Roland, Stan Sill, Paul Simson, and Bill Smunk
2. Teams that finished 20th or better at the 2020 Carolinas Senior Four-Ball Championship.
Jim Aughtry, Geno Berchiatti, Patrick Brady, Sherrill Britt, David Brown, Dean Channell, Ron Clontz, Dave Davis, Donald Detweiler, Preston Edmondson, Johnny Elam, Lee Forbis, Ryan Fox, Mike Gentry, Mike Gravley, Eddie Hargett, Todd Hendley, William Jamieson, Paul Jett, Jim Johnson, Steve Kidd, Kevin King, Robby Kirby, Mark Kozel, Nolan Mills III, Neal Morrison, Bill Morrissett, Frederick Nimmer, Doug Owens, Charlie Parks, Bill Plyler, Doug Ramey, Brian Reep, Gary Robinson, John Rudolph, Stan Sill, Paul Simson, Linley Tate, Julian Taylor, Pat Thompson, Walter Todd, Keith Waters
3. Players who competed in a 2020 USGA Championship or qualified for cancelled 2020 US Four-Ball.
Bubba Aughtry, Steve Harwell
4. One exemption for the championship host club.
5. Special exemption bestowed by the CGA.